SH2db - PTPN6 protein entry

PTPN6

Recommended name: Tyrosine-protein phosphatase non-receptor type 6

Gene name: PTPN6

No. of SH2 domains: 2

Uniprot: P29350

Sequences

Protein	Domain	N-term																						bA				bAaA		aA													aAbB		bB								bBbC					bC								bCbD											bD										bDbE		bE			bEbF				bF			bFaB	aB												C-term
																								x50	x51	x52	x53			x42	x43	x44	x45	x46	x47	x48	x49	x50	x51	x52	x53	x54			x45	x46	x47	x48	x49	x50	x51	x52	x49	x50				x47	x48	x49	x50	x51	x52	x53	x54												x47	x48	x49	x50	x51	x52	x53	x54	x55	x56			x48	x49	x50					x48	x49	x50		x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57
PTPN6	N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	M	V	R	W	F	H	R	D	L	S	G	L	D	A	E	T	L	L	K	G	R	G	V	H	G	S	F	L	A	R	P	S	R	K	N	Q	G	D	F	S	L	S	V	R	V	G	D	-	-	-	-	-	-	-	-	-	Q	V	T	H	I	R	I	Q	N	S	G	D	F	Y	D	L	Y	G	G	E	K	F	A	T	L	T	E	L	V	E	Y	Y	T	Q	Q	Q	G	V	L	Q	D	R	D	G	T	I	I	H	L	K	Y	P	L	N	C	S	D	P
PTPN6	C-terminal	D	R	D	G	T	I	I	H	L	K	Y	P	L	N	C	S	D	P	T	S	E	R	W	Y	H	G	H	M	S	G	G	Q	A	E	T	L	L	Q	A	K	G	E	P	W	T	F	L	V	R	E	S	L	S	Q	P	G	D	F	V	L	S	V	L	S	D	Q	P	K	A	G	P	G	S	P	L	R	V	T	H	I	K	V	M	C	E	G	G	R	Y	T	V	G	G	L	E	T	F	D	S	L	T	D	L	V	E	H	F	K	K	T	G	I	E	E	A	S	G	A	F	V	Y	L	R	Q	P	Y	Y	A	T	R	V	N	A

Structures


PDB	Type	Resolution	Domains	Chains	Publication date	Authors	Reference
P29350-AF	Alphafold	-	N-terminal C-terminal	A	2022-06-01	-	-
1X6C	Solution NMR	None	C-terminal	A	2005-11-17	Sato M., Koshiba S. ... Kigawa T., Yokoyama S.
2B3O	X-ray diffraction	2.800	C-terminal N-terminal	A	2005-10-25	Yang J., Liu L. ... Zhao Z.J., Zhou G.W.	10.1074/jbc.M210430200
2RMX	Solution NMR	None	C-terminal	A	2008-12-02	Koshiba S., Kasai T. ... Kigawa T., Yokoyama S.
2YU7	Solution NMR	None	C-terminal	A	2008-04-15	Kasai T., Koshiba S. ... Kigawa T., Yokoyama S.
3PS5	X-ray diffraction	3.100	C-terminal N-terminal	A	2011-04-20	Wang W., Liu L. ... Zhao Z.J., Zhou G.W.	10.1002/jcb.23125