Protein: PTPN6
Published: Oct. 25, 2005
Method: X-ray diffraction
Resolution: 2.800
Publication: Crystal structure of human protein-tyrosine phosphatase SHP-1.
| Protein | Domain | N-term | bA | bAaA | aA | aAbB | bB | bBbC | bC | bCbD | bD | bDbE | bE | bEbF | bF | bFaB | aB | C-term | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| x50 | x51 | x52 | x53 | x42 | x43 | x44 | x45 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x45 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x49 | x50 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x55 | x56 | x48 | x49 | x50 | x48 | x49 | x50 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x55 | x56 | x57 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| PTPN6 | N-terminal | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | M | V | R | W | F | H | R | D | L | S | G | L | D | A | E | T | L | L | K | G | R | G | V | H | G | S | F | L | A | R | P | S | R | K | N | Q | G | D | F | S | L | S | V | R | V | G | D | - | - | - | - | - | - | - | - | - | Q | V | T | H | I | R | I | Q | N | S | G | D | F | Y | D | L | Y | G | G | E | K | F | A | T | L | T | E | L | V | E | Y | Y | T | Q | Q | Q | G | V | L | Q | D | R | D | G | T | I | I | H | L | K | Y | P | L | N | C | S | D | P | |
| PTPN6 | 2B3O_N_A | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | V | R | W | F | H | R | D | L | S | G | L | D | A | E | T | L | L | K | G | R | G | V | H | G | S | F | L | A | R | P | S | R | K | N | Q | G | D | F | S | L | S | V | R | V | G | D | - | - | - | - | - | - | - | - | - | Q | V | T | H | I | R | I | Q | N | S | G | D | F | Y | D | L | Y | G | G | E | K | F | A | T | L | T | E | L | V | E | Y | Y | T | Q | Q | Q | G | V | L | Q | D | R | D | G | T | I | I | H | L | K | Y | P | L | N | C | S | D | P | |
| PTPN6 | C-terminal | D | R | D | G | T | I | I | H | L | K | Y | P | L | N | C | S | D | P | T | S | E | R | W | Y | H | G | H | M | S | G | G | Q | A | E | T | L | L | Q | A | K | G | E | P | W | T | F | L | V | R | E | S | L | S | Q | P | G | D | F | V | L | S | V | L | S | D | Q | P | K | A | G | P | G | S | P | L | R | V | T | H | I | K | V | M | C | E | G | G | R | Y | T | V | G | G | L | E | T | F | D | S | L | T | D | L | V | E | H | F | K | K | T | G | I | E | E | A | S | G | A | F | V | Y | L | R | Q | P | Y | Y | A | T | R | V | N | A | |
| PTPN6 | 2B3O_C_A | D | R | D | G | T | I | I | H | L | K | Y | P | L | N | C | S | D | P | T | S | E | R | W | Y | H | G | H | M | S | G | G | Q | A | E | T | L | L | Q | A | K | G | E | P | W | T | F | L | V | R | E | S | L | S | Q | P | G | D | F | V | L | S | V | L | S | D | Q | P | K | S | P | L | - | - | - | - | R | V | T | H | I | K | V | M | C | E | G | G | R | Y | T | V | G | G | L | E | T | F | D | S | L | T | D | L | V | E | H | F | K | K | T | G | I | E | E | A | S | G | A | F | V | Y | L | R | Q | P | Y | Y | A | T | R | V | N | A | |