PDB structure 5GJI


Protein: PIK3R1

Published: Dec. 14, 2016

Method: X-ray diffraction

Resolution: 0.900

Publication: Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins

Domains: N C

Chains: A

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Protein Domain N-term bA bAaA aA aAbB bB bBbC bC bCbD bD bDbE bE bEbF bF bFaB aB C-term
x50 x51 x52 x53 x42 x43 x44 x45 x46 x47 x48 x49 x50 x51 x45 x46 x47 x48 x49 x50 x51 x52 x49 x50 x47 x48 x49 x50 x51 x52 x53 x54 x47 x48 x49 x50 x51 x52 x53 x54 x55 x56 x48 x49 x50 x48 x49 x50 x46 x47 x48 x49 x50 x51 x52 x53 x54 x55 x56 x57
PIK3R1 N-terminal P P K P T T V A N N G M N N N M S L Q D A E W Y W G D I S R E E V N E K L R D T A D G T F L V R D A S T K M H G D Y T L T L R K G G N N K L I K I F H R D G K Y G F S D P - L T F S S V V E L I N H Y R N E S L A Q Y N P K L D V K L L Y P V S K Y Q Q D
PIK3R1 5GJI_N_A - - - - - - - - - - - - - S N M S L Q N A E W Y W G D I S R E E V N E K L R D T A D G T F L V R D A S T K M H G D Y T L T L R K G G N N K L I K I F H R D G K Y G F S D P - L T F S S V V E L I N H Y R N E S L A Q Y N P K L D V K L L Y P V S K - - - -
**
PIK3R1 C-terminal N T E D Q Y S L V E D D E D L P H H D E K T W N V G S S N R N K A E N L L R G K R D G T F L V R E S S K Q G - - C Y A C S V V V D G E V K H C V I N K T A T G Y G F A E P Y N L Y S S L K E L V L H Y Q H T S L V Q H N D S L N V T L A Y P V Y A Q Q R R