SH2db - 4ZOP structure entry

PDB structure 4ZOP

Protein: PIK3R1

Published: May 18, 2016

Method: X-ray diffraction

Resolution: 2.620

Publication: Co-crystal Structure of the Lipid Kinase PI3K alpha with a selective phosphatidylinositol-3 kinase alpha inhibitorCo-crystal Structure of the Lipid Kinase PI3K alpha with a selective phosphatidylinositol-3 kinase alpha inhibitor (to be published)

Protein	Domain	N-term																						bA				bAaA		aA										aAbB				bB								bBbC						bC								bCbD		bD										bDbE		bE			bEbF					bF			bFaB	aB												C-term

																								x50	x51	x52	x53			x42	x43	x44	x45	x46	x47	x48	x49	x50	x51					x45	x46	x47	x48	x49	x50	x51	x52	x49	x50					x47	x48	x49	x50	x51	x52	x53	x54			x47	x48	x49	x50	x51	x52	x53	x54	x55	x56			x48	x49	x50						x48	x49	x50		x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57
PIK3R1	N-terminal	P	P	K	P	T	T	V	A	N	N	G	M	N	N	N	M	S	L	Q	D	A	E	W	Y	W	G	D	I	S	R	E	E	V	N	E	K	L	R	D	T	A	D	G	T	F	L	V	R	D	A	S	T	K	M	H	G	D	Y	T	L	T	L	R	K	G	G	N	N	K	L	I	K	I	F	H	R	D	G	K	Y	G	F	S	D	P	-	L	T	F	S	S	V	V	E	L	I	N	H	Y	R	N	E	S	L	A	Q	Y	N	P	K	L	D	V	K	L	L	Y	P	V	S	K	Y	Q	Q	D
PIK3R1	4ZOP_N_B	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	M	S	L	Q	D	A	E	W	Y	W	G	D	I	S	R	E	E	V	N	E	K	L	R	D	T	A	D	G	T	F	L	V	R	D	A	S	-	-	-	-	-	D	Y	T	L	T	L	R	K	G	G	N	N	K	L	I	K	I	F	-	-	-	-	-	-	G	F	S	D	P	-	L	T	F	S	S	V	V	E	L	I	N	H	Y	R	-	-	L	L	Y	P	V	S	K	Y	Q	Q	D	-	-	-	-	-	-	-	-	-	-	-	-
PIK3R1	C-terminal	N	T	E	D	Q	Y	S	L	V	E	D	D	E	D	L	P	H	H	D	E	K	T	W	N	V	G	S	S	N	R	N	K	A	E	N	L	L	R	G	K	R	D	G	T	F	L	V	R	E	S	S	K	Q	G	-	-	C	Y	A	C	S	V	V	V	D	G	E	V	K	H	C	V	I	N	K	T	A	T	G	Y	G	F	A	E	P	Y	N	L	Y	S	S	L	K	E	L	V	L	H	Y	Q	H	T	S	L	V	Q	H	N	D	S	L	N	V	T	L	A	Y	P	V	Y	A	Q	Q	R	R

PDB structure 4ZOP

Domains: N C

Chains: B