Protein: SYK
Published: Nov. 28, 2012
Method: X-ray diffraction
Resolution: 2.190
Publication: Structural and biophysical characterization of the syk activation switch.
| Protein | Domain | N-term | bA | bAaA | aA | aAbB | bB | bBbC | bC | bCbD | bD | bDbE | bE | bEbF | bF | bFaB | aB | C-term | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| x50 | x51 | x52 | x53 | x42 | x43 | x44 | x45 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x45 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x49 | x50 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x55 | x56 | x48 | x49 | x50 | x48 | x49 | x50 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x55 | x56 | x57 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| SYK | N-terminal | - | - | - | - | - | - | - | - | M | A | S | S | G | M | A | D | S | A | N | H | L | P | F | F | F | G | N | I | T | R | E | E | A | E | D | Y | L | V | Q | G | G | M | S | D | G | L | Y | L | L | R | Q | S | R | N | Y | L | G | G | F | A | L | S | V | A | H | G | R | K | A | H | H | Y | T | I | E | R | E | L | N | G | T | Y | A | I | A | G | G | R | T | H | A | S | P | A | D | L | C | H | Y | H | S | Q | E | S | D | G | L | V | C | L | L | K | K | P | F | N | R | P | Q | G | V | Q | P | K | T | G | |
| SYK | 4FL2_N_A | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | S | A | N | H | L | P | F | F | F | G | N | I | T | R | E | E | A | E | D | Y | L | V | Q | G | G | M | S | D | G | L | Y | L | L | R | Q | S | R | N | Y | L | G | G | F | A | L | S | V | A | H | G | R | K | A | H | H | Y | T | I | E | R | E | L | N | G | T | Y | A | I | A | G | G | R | T | H | A | S | P | A | D | L | C | H | Y | H | S | Q | E | S | D | G | L | V | C | L | L | K | K | P | F | N | R | P | Q | G | V | Q | P | K | T | G | |
| SYK | C-terminal | A | I | I | S | Q | K | P | Q | L | E | K | L | I | A | T | T | A | H | E | K | M | P | W | F | H | G | K | I | S | R | E | E | S | E | Q | I | V | L | I | G | S | K | T | N | G | K | F | L | I | R | A | R | D | N | N | G | - | S | Y | A | L | C | L | L | H | E | G | K | V | L | H | Y | R | I | D | K | D | K | T | G | K | L | S | I | P | E | G | K | K | F | D | T | L | W | Q | L | V | E | H | Y | S | Y | K | A | D | G | L | L | R | V | L | T | V | P | C | Q | K | I | G | T | Q | G | N | V | N | F | |
| SYK | 4FL2_C_A | A | I | I | S | Q | K | P | Q | L | E | K | L | I | A | T | T | A | H | E | K | M | P | W | F | H | G | K | I | S | R | E | E | S | E | Q | I | V | L | I | G | S | K | T | N | G | K | F | L | I | R | A | R | D | N | N | G | - | S | Y | A | L | C | L | L | H | E | G | K | V | L | H | Y | R | I | D | K | D | K | T | G | K | L | S | I | P | E | G | K | K | F | D | T | L | W | Q | L | V | E | H | Y | S | Y | K | A | D | G | L | L | R | V | L | T | V | P | C | Q | K | I | G | T | - | - | - | - | - | - | |