Protein: ZAP70
Published: May 22, 2007
Method: X-ray diffraction
Resolution: 2.600
Publication: Structural Basis for the Inhibition of Tyrosine Kinase Activity of ZAP-70.
| Protein | Domain | N-term | bA | bAaA | aA | aAbB | bB | bBbC | bC | bCbD | bD | bDbE | bE | bEbF | bF | bFaB | aB | C-term | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| x50 | x51 | x52 | x53 | x42 | x43 | x44 | x45 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x45 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x49 | x50 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x55 | x56 | x48 | x49 | x50 | x48 | x49 | x50 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x55 | x56 | x57 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| ZAP70 | N-terminal | - | - | - | - | - | - | - | - | - | - | - | - | - | M | P | D | P | A | A | H | L | P | F | F | Y | G | S | I | S | R | A | E | A | E | E | H | L | K | L | A | G | M | A | D | - | G | L | F | L | L | R | Q | C | L | R | S | L | G | G | Y | V | L | S | L | V | H | D | V | R | F | H | H | F | P | I | E | R | Q | L | N | G | T | Y | A | I | A | G | G | K | A | H | C | - | G | P | A | E | L | C | E | F | Y | S | R | D | P | D | G | L | P | C | N | L | R | K | P | C | N | R | P | S | G | L | E | P | Q | P | G | |
| ZAP70 | 2OZO_N_A | - | - | - | - | - | - | - | - | - | - | - | - | - | - | P | D | P | A | A | H | L | P | F | F | Y | G | S | I | S | R | A | E | A | E | E | H | L | K | L | A | G | M | A | D | - | G | L | F | L | L | R | Q | C | L | R | S | L | G | G | Y | V | L | S | L | V | H | D | V | R | F | H | H | F | P | I | E | R | Q | L | N | G | T | Y | A | I | A | G | G | K | A | H | C | - | G | P | A | E | L | C | E | F | Y | S | R | D | P | D | G | L | P | C | N | L | R | K | P | C | N | R | P | S | G | L | E | P | Q | P | G | |
| ZAP70 | C-terminal | A | I | I | S | Q | A | P | Q | V | E | K | L | I | A | T | T | A | H | E | R | M | P | W | Y | H | S | S | L | T | R | E | E | A | E | R | K | L | Y | S | - | G | A | Q | T | D | G | K | F | L | L | R | P | R | K | E | Q | G | - | T | Y | A | L | S | L | I | Y | G | K | T | V | Y | H | Y | L | I | S | Q | D | K | A | G | K | Y | C | I | P | E | G | - | T | K | F | D | T | L | W | Q | L | V | E | Y | L | K | L | K | A | D | G | L | I | Y | C | L | K | E | A | C | P | N | S | S | A | S | N | A | S | G | A | |