SH2db - ZAP70 protein entry

ZAP70

Recommended name: Tyrosine-protein kinase ZAP-70

Gene name: ZAP70

No. of SH2 domains: 2

Uniprot: P43403

Sequences

Protein	Domain	N-term																						bA				bAaA		aA												aAbB					bB								bBbC					bC								bCbD		bD										bDbE			bE			bEbF					bF			bFaB	aB												C-term
																								x50	x51	x52	x53			x42	x43	x44	x45	x46	x47	x48	x49	x50	x51	x52	x53						x45	x46	x47	x48	x49	x50	x51	x52	x49	x50				x47	x48	x49	x50	x51	x52	x53	x54			x47	x48	x49	x50	x51	x52	x53	x54	x55	x56				x48	x49	x50						x48	x49	x50		x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57
ZAP70	N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	-	M	P	D	P	A	A	H	L	P	F	F	Y	G	S	I	S	R	A	E	A	E	E	H	L	K	L	A	G	M	A	D	-	G	L	F	L	L	R	Q	C	L	R	S	L	G	G	Y	V	L	S	L	V	H	D	V	R	F	H	H	F	P	I	E	R	Q	L	N	G	T	Y	A	I	A	G	G	K	A	H	C	-	G	P	A	E	L	C	E	F	Y	S	R	D	P	D	G	L	P	C	N	L	R	K	P	C	N	R	P	S	G	L	E	P	Q	P	G
ZAP70	C-terminal	A	I	I	S	Q	A	P	Q	V	E	K	L	I	A	T	T	A	H	E	R	M	P	W	Y	H	S	S	L	T	R	E	E	A	E	R	K	L	Y	S	-	G	A	Q	T	D	G	K	F	L	L	R	P	R	K	E	Q	G	-	T	Y	A	L	S	L	I	Y	G	K	T	V	Y	H	Y	L	I	S	Q	D	K	A	G	K	Y	C	I	P	E	G	-	T	K	F	D	T	L	W	Q	L	V	E	Y	L	K	L	K	A	D	G	L	I	Y	C	L	K	E	A	C	P	N	S	S	A	S	N	A	S	G	A

Structures


PDB	Type	Resolution	Domains	Chains	Publication date	Authors	Reference
P43403-AF	Alphafold	-	N-terminal C-terminal	A	2022-06-01	-	-
1M61	X-ray diffraction	2.500	N-terminal	A	2003-07-15	Folmer R.H.A., Geschwindner S., Xue Y.	10.1021/bi026465e
2OQ1	X-ray diffraction	1.900	N-terminal	A	2007-03-06	Hatada M.H., Lu X. ... Ram M.K., Theriault K.	10.1038/377032a0
2OZO	X-ray diffraction	2.600	N-terminal	A	2007-05-22	Deindl S., Kadlecek T.A. ... Weiss A., Kuriyan J.	10.1016/j.cell.2007.03.039
4K2R	X-ray diffraction	3.000	N-terminal	A	2013-05-08	Yan Q., Barros T. ... Weiss A., Kuriyan J.	10.1128/MCB.01637-12
4XZ0	X-ray diffraction	2.000	N-terminal	A	2015-06-17	Visperas P.R., Winger J.A. ... Weiss A., Kuriyan J.	10.1042/BJ20140793
4XZ1	X-ray diffraction	2.800	N-terminal	A	2015-07-29	Visperas P.R., Winger J.A. ... Weiss A., Kuriyan J.	10.1042/BJ20140793