Protein: LCK
Published: Oct. 21, 1998
Method: X-ray diffraction
Resolution: 1.900
Publication: Carboxymethyl-phenylalanine as a replacement for phosphotyrosine in SH2 domain binding.
| Protein | Domain | N-term | bA | bAaA | aA | aAbB | bB | bBbC | bC | bCbD | bD | bDbE | bE | bEbF | bF | bFaB | aB | C-term | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| x50 | x51 | x52 | x53 | x42 | x43 | x44 | x45 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x45 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x49 | x50 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x55 | x56 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x55 | x56 | x48 | x49 | x50 | x48 | x49 | x50 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x55 | x56 | x57 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| LCK | N-terminal | T | G | Q | E | G | F | I | P | F | N | F | V | A | K | A | N | S | L | E | P | E | P | W | F | F | K | N | L | S | R | K | D | A | E | R | Q | L | L | A | P | G | N | T | H | G | S | F | L | I | R | E | S | E | S | T | A | G | S | F | S | L | S | V | R | D | F | D | Q | N | Q | G | E | V | V | K | H | Y | K | I | R | N | L | D | N | G | G | F | Y | I | S | P | R | I | T | F | P | G | L | H | E | L | V | R | H | Y | T | N | A | S | D | G | L | C | T | R | L | S | R | P | C | Q | T | Q | K | P | Q | K | P | W | W | E | |
| LCK | 1BHH_N_A | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | E | P | E | P | W | F | F | K | N | L | S | R | K | D | A | E | R | Q | L | L | A | P | G | N | T | H | G | S | F | L | I | R | E | S | E | S | T | A | G | S | F | S | L | S | V | R | D | F | D | Q | N | Q | G | E | V | V | K | H | Y | K | I | R | N | L | D | N | G | G | F | Y | I | S | P | R | I | T | F | P | G | L | H | E | L | V | R | H | Y | T | N | A | S | D | G | L | C | T | R | L | S | R | P | C | Q | T | - | - | - | - | - | - | - | - | - | |
| LCK | 1BHH_N_B | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | P | E | P | W | F | F | K | N | L | S | R | K | D | A | E | R | Q | L | L | A | P | G | N | T | H | G | S | F | L | I | R | E | S | E | S | T | A | G | S | F | S | L | S | V | R | D | F | D | Q | N | Q | G | E | V | V | K | H | Y | K | I | R | N | L | D | N | G | G | F | Y | I | S | P | R | I | T | F | P | G | L | H | E | L | V | R | H | Y | T | N | A | S | D | G | L | C | T | R | L | S | R | P | C | Q | T | - | - | - | - | - | - | - | - | - | |