SH2db - LCK protein entry

LCK

Recommended name: Tyrosine-protein kinase Lck

Gene name: LCK

No. of SH2 domains: 1

Uniprot: P06239

Sequences

Protein	Domain	N-term																						bA				bAaA		aA											aAbB					bB								bBbC					bC										bCbD				bD											bDbE			bE			bEbF				bF			bFaB	aB												C-term
																								x50	x51	x52	x53			x42	x43	x44	x45	x46	x47	x48	x49	x50	x51	x52						x45	x46	x47	x48	x49	x50	x51	x52	x49	x50				x47	x48	x49	x50	x51	x52	x53	x54	x55	x56					x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56				x48	x49	x50					x48	x49	x50		x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57
LCK	N-terminal	T	G	Q	E	G	F	I	P	F	N	F	V	A	K	A	N	S	L	E	P	E	P	W	F	F	K	N	L	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	T	H	G	S	F	L	I	R	E	S	E	S	T	A	G	S	F	S	L	S	V	R	D	F	D	Q	N	Q	G	E	V	V	K	H	Y	K	I	R	N	L	D	N	G	G	F	Y	I	S	P	R	I	T	F	P	G	L	H	E	L	V	R	H	Y	T	N	A	S	D	G	L	C	T	R	L	S	R	P	C	Q	T	Q	K	P	Q	K	P	W	W	E

Structures


PDB	Type	Resolution	Domains	Chains	Publication date	Authors	Reference
P06239-AF	Alphafold	-	N-terminal	A	2022-06-01	-	-
1BHF	X-ray diffraction	1.800	N-terminal	A	1998-10-21	Tong L., Warren T.C. ... Proudfoot J.R., Jakes S.	10.1074/jbc.273.32.20238
1BHH	X-ray diffraction	1.900	N-terminal	A B	1998-10-21	Tong L., Warren T.C. ... Proudfoot J.R., Jakes S.	10.1074/jbc.273.32.20238
1CWD	X-ray diffraction	2.250	N-terminal	L	1996-12-07	Mikol V., Baumann G. ... Manning U., Zurini M.G.	10.1006/jmbi.1994.0089
1CWE	X-ray diffraction	2.300	N-terminal	A C	1996-12-07	Mikol V., Baumann G. ... Manning U., Zurini M.G.	10.1006/jmbi.1994.0089
1FBZ	X-ray diffraction	2.400	N-terminal	A B	2000-08-23	Shakespeare W., Yang M. ... Weigele M., Sawyer T.	10.1073/pnas.97.17.9373
1IJR	X-ray diffraction	2.200	N-terminal	A	2002-05-01	Kawahata N., Yang M.G. ... Bohacek R.S., Sawyer T.K.	10.1016/S0960-894X(01)00446-2
1LCJ	X-ray diffraction	1.800	N-terminal	A	1995-10-15	Eck M.J., Shoelson S.E., Harrison S.C.	10.1038/362087a0
1LCK	X-ray diffraction	2.500	N-terminal	A	1995-10-15	Eck M.J., Atwell S.K., Shoelson S.E., Harrison S.C.	10.1038/368764a0
1LKK	X-ray diffraction	1.000	N-terminal	A	1996-03-08	Tong L., Warren T.C. ... Rose J., Jakes S.	10.1006/jmbi.1996.0112
1LKL	X-ray diffraction	1.800	N-terminal	A	1996-03-08	Tong L., Warren T.C. ... Rose J., Jakes S.	10.1006/jmbi.1996.0112
1X27	X-ray diffraction	2.700	N-terminal	A B C D E F	2006-02-07	Nasertorabi F., Tars K. ... Vuori K., Ely K.R.	10.1002/jmr.755
4D8K	X-ray diffraction	2.360	N-terminal	A	2012-01-25	Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology
5MTM	X-ray diffraction	2.405	N-terminal	A	2017-04-05	Kukenshoner T., Schmit N.E. ... Koide S., Hantschel O.	10.1016/j.jmb.2017.03.023
5MTN	X-ray diffraction	2.850	N-terminal	A	2017-04-05	Kukenshoner T., Schmit N.E. ... Koide S., Hantschel O.	10.1016/j.jmb.2017.03.023