SH2db - STAT3 protein entry

STAT3

Recommended name: Signal transducer and activator of transcription 3

Gene name: STAT3

No. of SH2 domains: 1

Uniprot: P40763

Sequences

Protein	Domain	N-term																							bA				bAaA		aA												aAbB		bB								bBbC						bC										bCbD		bD											aB'								aB									C-term
																									x50	x51	x52	x53			x42	x43	x44	x45	x46	x47	x48	x49	x50	x51	x52	x53			x45	x46	x47	x48	x49	x50	x51	x52	x49	x50					x47	x48	x49	x50	x51	x52	x53	x54	x55	x56			x44	x45	x46	x47	x48	x49	x50	x51	x52	x521	x53	x45	x46	x47	x48	x49	x50	x51	x52	x46	x47	x48	x49	x50	x51	x52	x53	x54
STAT3	N-terminal	F	W	V	W	L	D	N	I	I	D	L	V	K	K	Y	I	L	A	L	W	N	E	G	Y	I	M	G	F	I	S	K	E	R	E	R	A	I	L	S	T	K	P	P	G	T	F	L	L	R	F	S	E	S	S	K	E	G	G	V	T	F	T	W	V	E	K	D	I	S	G	K	T	Q	I	Q	S	V	E	P	Y	T	K	Q	Q	L	N	N	M	S	F	A	E	I	I	M	G	Y	K	I	M	D	A	T	N	I	L	V	S	P	L	V	Y	L	Y	P	D	I	P	K	E	E	A	F

Structures


PDB	Type	Resolution	Domains	Chains	Publication date	Authors	Reference
P40763-AF	Alphafold	-	N-terminal	A	2022-06-01	-	-
6TLC	X-ray diffraction	2.900	N-terminal	A B	2020-07-22	La Sala G., Michiels C. ... Dumoutier L., Hantschel O.	10.1038/s41467-020-17920-z
6NUQ	X-ray diffraction	3.150	N-terminal	A	2019-12-04	Bai L., Zhou H. ... Stuckey J.A., Wang S.	10.1016/j.ccell.2019.10.002
6NJS	X-ray diffraction	2.700	N-terminal	A	2019-12-04	Bai L., Zhou H. ... Stuckey J.A., Wang S.	10.1016/j.ccell.2019.10.002
6QHD	X-ray diffraction	2.850	N-terminal	A B	2019-06-19	Belo Y., Mielko Z. ... Gordan R., Arbely E.	10.1016/j.bbagen.2019.05.019