SH2db - SOCS2 protein entry

SOCS2

Recommended name: Suppressor of cytokine signaling 2

Gene name: SOCS2

No. of SH2 domains: 1

Uniprot: O14508

Sequences

Protein	Domain	N-term																						bA				bAaA		aA										aAbB				bB								bBbC					bC								bCbD		bD										bDbE		bE			bEbF											bF			bFaB	aB														C-term
																								x50	x51	x52	x53			x42	x43	x44	x45	x46	x47	x48	x49	x50	x51					x45	x46	x47	x48	x49	x50	x51	x52	x49	x50				x47	x48	x49	x50	x51	x52	x53	x54			x47	x48	x49	x50	x51	x52	x53	x54	x55	x56			x48	x49	x50												x48	x49	x50		x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57	x58	x59
SOCS2	N-terminal	A	E	E	P	S	P	Q	A	A	R	L	A	K	A	L	R	E	L	G	Q	T	G	W	Y	W	G	S	M	T	V	N	E	A	K	E	K	L	K	E	A	P	E	G	T	F	L	I	R	D	S	S	H	S	D	Y	L	L	T	I	S	V	K	T	S	A	G	P	T	N	L	R	I	E	Y	Q	D	G	K	F	R	L	D	S	I	I	C	V	K	S	K	L	K	Q	F	D	S	V	V	H	L	I	D	Y	Y	V	Q	M	C	K	D	K	R	T	G	P	E	A	P	R	N	G	T	V	H	L	Y	L	T	K	P

Structures


PDB	Type	Resolution	Domains	Chains	Publication date	Authors	Reference
O14508-AF	Alphafold	-	N-terminal	A	2022-06-01	-	-
7M6T	X-ray diffraction	3.194	N-terminal	A	2021-10-13	Linossi E.M., Li K. ... Kershaw N.J., Nicholson S.E.	10.1038/s41467-021-26983-5
2C9W	X-ray diffraction	1.900	N-terminal	A	2006-02-22	Bullock A.N., Debreczeni J.E. ... Sundstrom M., Knapp S.	10.1073/pnas.0601638103
4JGH	X-ray diffraction	3.000	N-terminal	A	2013-08-07	Kim Y.K., Kwak M.J. ... Jung J.U., Oh B.H.	10.1107/S0907444913011220
5BO4	X-ray diffraction	2.900	N-terminal	A D G J M P	2015-07-08	Gadd M.S., Bulatov E., Ciulli A.	10.1371/journal.pone.0131218
6I4X	X-ray diffraction	2.690	N-terminal	A	2019-05-29	Kung W.W., Ramachandran S. ... Bruno E., Ciulli A.	10.1038/s41467-019-10190-4
6I5J	X-ray diffraction	2.800	N-terminal	A D	2019-05-29	Kung W.W., Ramachandran S. ... Bruno E., Ciulli A.	10.1038/s41467-019-10190-4
6I5N	X-ray diffraction	1.980	N-terminal	A D	2019-05-29	Kung W.W., Ramachandran S. ... Bruno E., Ciulli A.	10.1038/s41467-019-10190-4