SH2db - GRB7 protein entry

GRB7

Recommended name: Growth factor receptor-bound protein 7

Gene name: GRB7

No. of SH2 domains: 1

Uniprot: Q14451

Sequences

Protein	Domain	N-term																						bA				bAaA		aA													aAbB			bB								bBbC					bC								bCbD		bD											bDbE			bE			bEbF							bF			bFaB	aB												C-term
																								x50	x51	x52	x53			x42	x43	x44	x45	x46	x47	x48	x49	x50	x51	x52	x53	x54				x45	x46	x47	x48	x49	x50	x51	x52	x49	x50				x47	x48	x49	x50	x51	x52	x53	x54			x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57				x48	x49	x50								x48	x49	x50		x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57
GRB7	N-terminal	R	L	S	L	P	M	P	A	S	G	T	S	L	S	A	A	I	H	R	T	Q	L	W	F	H	G	R	I	S	R	E	E	S	Q	R	L	I	G	Q	Q	G	L	V	D	G	L	F	L	V	R	E	S	Q	R	N	P	Q	G	F	V	L	S	L	C	H	L	Q	K	V	K	H	Y	L	I	L	P	S	E	E	E	G	R	L	Y	F	S	M	D	D	G	Q	T	R	F	T	D	L	L	Q	L	V	E	F	H	Q	L	N	R	G	I	L	P	C	L	L	R	H	C	C	T	R	V	A	L

Structures


PDB	Type	Resolution	Domains	Chains	Publication date	Authors	Reference
Q14451-AF	Alphafold	-	N-terminal	A	2022-06-01	-	-
1MW4	Solution NMR	None	N-terminal	A	2003-09-09	Ivancic M., Daly R.J., Lyons B.A.	10.1023/A:1025498409113
2L4K	Solution NMR	None	N-terminal	A	2010-11-17	Pias S.C., Johnson D.L., Smith D.E., Lyons B.A.
2QMS	X-ray diffraction	2.100	N-terminal	A B C D	2008-07-22	Porter C.J., Matthews J.M. ... Wilce M.C., Wilce J.A.	10.1186/1472-6807-7-58
3PQZ	X-ray diffraction	2.413	N-terminal	A B C D	2011-07-20	Ambaye N.D., Pero S.C. ... Wilce M.C., Wilce J.A.	10.1016/j.jmb.2011.07.030
4WWQ	X-ray diffraction	1.800	N-terminal	A B	2015-09-23	Watson G.M., Gunzburg M.J. ... Wilce M.C., Wilce J.A.	10.1021/acs.jmedchem.5b00609
4X6S	X-ray diffraction	2.550	N-terminal	A B	2015-09-23	Watson G.M., Gunzburg M.J. ... Wilce M.C., Wilce J.A.	10.1021/acs.jmedchem.5b00609
5D0J	X-ray diffraction	2.600	N-terminal	A B C D	2016-06-15	Gunzburg M.J., Kulkarni K. ... Wilce M.C., Wilce J.A.	10.1038/srep27060
5EEL	X-ray diffraction	2.470	N-terminal	A B C D E F	2016-06-15	Gunzburg M.J., Kulkarni K. ... Wilce M.C., Wilce J.A.	10.1038/srep27060
5EEQ	X-ray diffraction	1.600	N-terminal	A B	2016-06-15	Gunzburg M.J., Kulkarni K. ... Wilce M.C., Wilce J.A.	10.1038/srep27060
5TYI	X-ray diffraction	2.150	N-terminal	A B C D	2017-11-15	Watson G.M., Kulkarni K. ... Wilce M.C.J., Wilce J.A.	10.1021/acs.jmedchem.7b01320
5U06	X-ray diffraction	2.100	N-terminal	A B C D	2017-11-15	Watson G.M., Kulkarni K. ... Wilce M.C.J., Wilce J.A.	10.1021/acs.jmedchem.7b01320
5U1Q	X-ray diffraction	2.100	N-terminal	A B C D	2017-11-15	Watson G.M., Kulkarni K. ... Wilce M.C.J., Wilce J.A.	10.1021/acs.jmedchem.7b01320