SH2db - FES protein entry

FES

Recommended name: Tyrosine-protein kinase Fes/Fps

Gene name: FES

No. of SH2 domains: 1

Uniprot: P07332

Sequences

Protein	Domain	N-term																						bA				bAaA		aA											aAbB	bB								bBbC				bC								bCbD		bD										bDbE		bE			bEbF			bF			bFaB	aB												C-term
																								x50	x51	x52	x53			x42	x43	x44	x45	x46	x47	x48	x49	x50	x51	x52		x45	x46	x47	x48	x49	x50	x51	x52	x49	x50			x47	x48	x49	x50	x51	x52	x53	x54			x47	x48	x49	x50	x51	x52	x53	x54	x55	x56			x48	x49	x50				x48	x49	x50		x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57
FES	N-terminal	K	F	S	L	P	P	P	L	Q	L	I	P	E	V	Q	K	P	L	H	E	Q	L	W	Y	H	G	A	I	P	R	A	E	V	A	E	L	L	V	H	S	G	D	F	L	V	R	E	S	Q	G	K	Q	E	Y	V	L	S	V	L	W	D	G	L	P	R	H	F	I	I	Q	S	L	D	N	L	Y	R	L	E	G	E	G	F	P	S	I	P	L	L	I	D	H	L	L	S	T	Q	Q	P	L	T	K	K	S	G	V	V	L	H	R	A	V	P	K	D	K	W	V	L

Structures


PDB	Type	Resolution	Domains	Chains	Publication date	Authors	Reference
P07332-AF	Alphafold	-	N-terminal	A	2022-06-01	-	-
7T1L	X-ray diffraction	1.350	N-terminal	A B	2022-08-24	Martyn G.D., Veggiani G. ... Moritz R.L., Sidhu S.S.	10.1021/acschembio.2c00051
7T1K	X-ray diffraction	1.250	N-terminal	A	2022-08-24	Martyn G.D., Veggiani G. ... Moritz R.L., Sidhu S.S.	10.1021/acschembio.2c00051
1WQU	Solution NMR	None	N-terminal	A	2005-06-14	Scott A., Pantoja-Uceda D. ... Yokoyama S., Guntert P.	10.1007/s10858-005-0946-6
2DCR	Solution NMR	None	N-terminal	A	2006-10-17	Lopez-Mendez B., Guntert P.	10.1021/ja061136l
3BKB	X-ray diffraction	1.780	N-terminal	A	2007-12-25	Filippakopoulos P., Kofler M. ... Pawson T., Knapp S.	10.1016/j.cell.2008.07.047
3CBL	X-ray diffraction	1.750	N-terminal	A	2008-03-04	Filippakopoulos P., Kofler M. ... Pawson T., Knapp S.	10.1016/j.cell.2008.07.047
3CD3	X-ray diffraction	1.980	N-terminal	A	2008-03-25	Filippakopoulos P., Kofler M. ... Pawson T., Knapp S.	10.1016/j.cell.2008.07.047
4E93	X-ray diffraction	1.840	N-terminal	A	2012-04-18	Hellwig S., Miduturu C.V. ... Gray N.S., Smithgall T.E.	10.1016/j.chembiol.2012.01.020
6JMF	X-ray diffraction	2.000	N-terminal	A	2019-06-12	Taniguchi T., Inagaki H. ... Imaoka T., Nakayama K.	10.1021/acsmedchemlett.8b00631