SH2db - ABL1 protein entry

ABL1

Recommended name: Tyrosine-protein kinase ABL1

Gene name: ABL1

No. of SH2 domains: 1

Uniprot: P00519

Sequences

Protein	Domain	N-term																						bA				bAaA		aA												aAbB		bB								bBbC					bC								bCbD		bD										bDbE			bE			bEbF				bF			bFaB	aB												C-term
																								x50	x51	x52	x53			x42	x43	x44	x45	x46	x47	x48	x49	x50	x51	x52	x53			x45	x46	x47	x48	x49	x50	x51	x52	x49	x50				x47	x48	x49	x50	x51	x52	x53	x54			x47	x48	x49	x50	x51	x52	x53	x54	x55	x56				x48	x49	x50					x48	x49	x50		x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57
ABL1	N-terminal	K	N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	N	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	S	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	R	S	I	S	L	R	Y	E	G	R	V	Y	H	Y	R	I	N	T	A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	I	T	T	L	H	Y	P	A	P	K	R	N	K	P	T	V	Y	G	V

Structures


PDB	Type	Resolution	Domains	Chains	Publication date	Authors	Reference
P00519-AF	Alphafold	-	N-terminal	A	2022-06-01	-	-
1AB2	Solution NMR	None	N-terminal	A	1994-01-31	Overduin M., Rios C.B. ... Baltimore D., Cowburn D.	10.1016/0092-8674(92)90437-H
1OPL	X-ray diffraction	3.420	N-terminal	A B	2003-04-08	Nagar B., Hantschel O. ... Superti-Furga G., Kuriyan J.	10.1016/S0092-8674(03)00194-6
2ABL	X-ray diffraction	2.500	N-terminal	A	1997-09-04	Nam H.J., Haser W.G., Roberts T.M., Frederick C.A.	10.1016/S0969-2126(96)00116-5
2FO0	X-ray diffraction	2.270	N-terminal	A	2006-03-21	Nagar B., Hantschel O. ... Superti-Furga G., Kuriyan J.	10.1016/j.molcel.2006.01.035
3K2M	X-ray diffraction	1.750	N-terminal	A B	2010-03-31	Wojcik J., Hantschel O. ... Superti-Furga G., Koide S.	10.1038/nsmb.1793
3T04	X-ray diffraction	2.100	N-terminal	A	2011-11-23	Grebien F., Hantschel O. ... Koide S., Superti-Furga G.	10.1016/j.cell.2011.08.046
3UYO	X-ray diffraction	1.830	N-terminal	A	2011-12-28	Koide A., Wojcik J. ... Hoey R.J., Koide S.	10.1016/j.jmb.2011.12.019
4XEY	X-ray diffraction	2.891	N-terminal	B	2015-04-01	Lorenz S., Deng P. ... Superti-Furga G., Kuriyan J.	10.1042/BJ20141492
5DC0	X-ray diffraction	2.230	N-terminal	B	2016-03-02	Wojcik J., Lamontanara A.J. ... Hantschel O., Koide S.	10.1074/jbc.M115.707901
5DC4	X-ray diffraction	1.480	N-terminal	A	2016-03-02	Wojcik J., Lamontanara A.J. ... Hantschel O., Koide S.	10.1074/jbc.M115.707901
5DC9	X-ray diffraction	1.560	N-terminal	A	2016-03-02	Wojcik J., Lamontanara A.J. ... Hantschel O., Koide S.	10.1074/jbc.M115.707901
5MO4	X-ray diffraction	2.170	N-terminal	A	2017-04-05	Wylie A.A., Schoepfer J. ... Keen N.J., Sellers W.R.	10.1038/nature21702
6AMV	Solution NMR	None	N-terminal	A	2017-09-27	Saleh T., Rossi P., Kalodimos C.G.	10.1038/nsmb.3470
6AMW	Solution NMR	None	N-terminal	A	2017-09-27	Saleh T., Rossi P., Kalodimos C.G.	10.1038/nsmb.3470