PDB structure 3VS7


Protein: HCK

Published: May 1, 2013

Method: X-ray diffraction

Resolution: 3.001

Publication: A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo

Domains: N

Chains: A B

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Protein Domain N-term bA bAaA aA aAbB bB bBbC bC bCbD bD bDbE bE bEbF bF bFaB aB C-term
x50 x51 x52 x53 x42 x43 x44 x45 x46 x47 x48 x49 x50 x51 x52 x45 x46 x47 x48 x49 x50 x51 x52 x49 x50 x47 x48 x49 x50 x51 x52 x53 x54 x55 x56 x44 x45 x46 x47 x48 x49 x50 x51 x52 x53 x54 x55 x56 x48 x49 x50 x48 x49 x50 x46 x47 x48 x49 x50 x51 x52 x53 x54 x55 x56 x57
HCK N-terminal T R K E G Y I P S N Y V A R V D S L E T E E W F F K G I S R K D A E R Q L L A P G N M L G S F M I R D S E T T K G S Y S L S V R D Y D P R Q G D T V K H Y K I R T L D N G G F Y I S P R S T F S T L Q E L V D H Y K K G N D G L C Q K L S V P C M S S K P Q K P W E K
HCK 3VS7_N_A T R K E G Y I P S N Y V A R V D S L E T E E W F F K G I S R K D A E R Q L L A P G N M L G S F M I R D S E T T K G S Y S L S V R D Y D P R Q G D T V K H Y K I R T L D N G G F Y I S P R S T F S T L Q E L V D H Y K K G N D G L C Q K L S V P C M S S K P Q K - - - -
HCK 3VS7_N_B T R K E G Y I P S N Y V A R V D S L E T E E W F F K G I S R K D A E R Q L L A P G N M L G S F M I R D S E T T K G S Y S L S V R D Y D P R Q G D T V K H Y K I R T - - - - - F Y I S P R S T F S T L Q E L V D H Y K K G N D G L C Q K L S V P C M S S K P Q K - - - -