Protein: GRB2
Published: March 13, 2002
Method: X-ray diffraction
Resolution: 2.000
Publication: Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.
| Protein | Domain | N-term | bA | bAaA | aA | aAbB | bB | bBbC | bC | bCbD | bD | bDbE | bE | bEbF | bF | bFaB | aB | C-term | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| x50 | x51 | x52 | x53 | x42 | x43 | x44 | x45 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x45 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x49 | x50 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x55 | x56 | x48 | x49 | x50 | x48 | x49 | x50 | x46 | x47 | x48 | x49 | x50 | x51 | x52 | x53 | x54 | x55 | x56 | x57 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRB2 | N-terminal | K | A | E | L | N | G | K | D | G | F | I | P | K | N | Y | I | E | M | K | P | H | P | W | F | F | G | K | I | P | R | A | K | A | E | E | M | L | S | K | Q | R | H | D | G | A | F | L | I | R | E | S | E | S | A | P | G | D | F | S | L | S | V | K | F | G | N | D | V | Q | H | F | K | V | L | R | D | G | A | G | K | Y | F | L | W | V | V | K | F | N | S | L | N | E | L | V | D | Y | H | R | S | T | S | V | S | R | N | Q | Q | I | F | L | R | D | I | E | Q | V | P | Q | Q | P | T | Y | V | |
| GRB2 | 1JYQ_N_A | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | G | S | M | A | W | F | F | G | K | I | P | R | A | K | A | E | E | M | L | S | K | Q | R | H | D | G | A | F | L | I | R | E | S | E | S | A | P | G | D | F | S | L | S | V | K | F | G | N | D | V | Q | H | F | K | V | L | R | D | G | A | G | K | Y | F | L | W | V | V | K | F | N | S | L | N | E | L | V | D | Y | H | R | S | T | S | V | S | R | N | Q | Q | I | F | L | R | D | I | - | - | - | - | - | - | - | - | - | - | |
| GRB2 | 1JYQ_N_B | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | G | S | M | A | W | F | F | G | K | I | P | R | A | K | A | E | E | M | L | S | K | Q | R | H | D | G | A | F | L | I | R | E | S | E | S | A | P | G | D | F | S | L | S | V | K | F | G | N | D | V | Q | H | F | K | V | L | R | D | G | A | G | K | Y | F | L | W | V | V | K | F | N | S | L | N | E | L | V | D | Y | H | R | S | T | S | V | S | R | N | Q | Q | I | F | L | R | D | I | - | - | - | - | - | - | - | - | - | - | |