SH2db - STAT1 protein entry

STAT1

Recommended name: Signal transducer and activator of transcription 1-alpha/beta

Gene name: STAT1

No. of SH2 domains: 1

Uniprot: P42224

Sequences

Protein	Domain	N-term																						bA				bAaA		aA									aAbB					bB								bBbC						bC										bCbD			bD											aB'								aB									C-term
																								x50	x51	x52	x53			x42	x43	x44	x45	x46	x47	x48	x49	x50						x45	x46	x47	x48	x49	x50	x51	x52	x49	x50					x47	x48	x49	x50	x51	x52	x53	x54	x55	x56				x44	x45	x46	x47	x48	x49	x50	x51	x52	x521	x53	x45	x46	x47	x48	x49	x50	x51	x52	x46	x47	x48	x49	x50	x51	x52	x53	x54
STAT1	N-terminal	W	L	W	I	E	S	I	L	E	L	I	K	K	H	L	L	P	L	W	N	D	G	C	I	M	G	F	I	S	K	E	R	E	R	A	L	L	K	D	Q	Q	P	G	T	F	L	L	R	F	S	E	S	S	R	E	G	A	I	T	F	T	W	V	E	R	S	Q	N	G	G	E	P	D	F	H	A	V	E	P	Y	T	K	K	E	L	S	A	V	T	F	P	D	I	I	R	N	Y	K	V	M	A	A	E	N	I	P	E	N	P	L	K	Y	L	Y	P	N	I	D	K	D	H	A	F	G	K	Y	Y	S	R	P	K	E	A	P	E	P	M	E

Structures


PDB	Type	Resolution	Domains	Chains	Publication date	Authors	Reference
P42224-AF	Alphafold	-	N-terminal	A	2022-06-01	-	-
8D3F	X-ray diffraction	2.970	N-terminal	A	2022-07-06	Huang Z., Liu H. ... Amarasinghe G.K., Sibley L.D.	10.1038/s41467-022-31720-7
7NUF	X-ray diffraction	2.000	N-terminal	A	2021-07-28	Talbot-Cooper C., Pantelejevs T. ... Hickman H.D., Smith G.L.	10.1016/j.chom.2022.01.014
1BF5	X-ray diffraction	2.900	N-terminal	A	1998-08-12	Chen X., Vinkemeier U. ... Darnell Jr. J.E., Kuriyan J.	10.1016/S0092-8674(00)81443-9
1YVL	X-ray diffraction	3.000	N-terminal	A B	2005-03-22	Mao X., Ren Z. ... Darnell J.E., Chen X.	10.1016/j.molcel.2005.02.021