SH2db - PLCG1 protein entry

PLCG1

Recommended name: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Gene name: PLCG1

No. of SH2 domains: 2

Uniprot: P19174

Sequences

Protein	Domain	N-term																						bA				bAaA						aA																		aAbB			bB								bBbC					bC								bCbD		bD												bDbE		bE					bEbF				bF			bFaB	aB												C-term
																								x50	x51	x52	x53							x41	x42	x43	x44	x45	x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57	x58				x45	x46	x47	x48	x49	x50	x51	x52	x49	x50				x47	x48	x49	x50	x51	x52	x53	x54			x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57	x58			x46	x47	x48	x49	x50					x48	x49	x50		x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57
PLCG1	N-terminal	G	N	E	D	E	E	E	P	K	E	V	S	S	S	T	E	L	H	S	N	E	K	W	F	H	G	K	L	G	A	G	R	D	G	R	H	I	A	E	R	L	L	T	E	Y	C	I	E	T	G	A	P	D	G	S	F	L	V	R	E	S	E	T	F	V	G	D	Y	T	L	S	F	W	R	N	G	K	V	Q	H	C	R	I	H	S	R	Q	D	A	G	T	P	K	F	F	L	T	D	N	L	V	F	D	S	L	Y	D	L	I	T	H	Y	Q	Q	V	P	L	R	C	N	E	F	E	M	R	L	S	E	P	V	P	Q	T	N	A	H	E	S
PLCG1	C-terminal	C	N	E	F	E	M	R	L	S	E	P	V	P	Q	T	N	A	H	E	S	K	E	W	Y	H	A	S	L	-	-	-	-	-	T	R	A	Q	A	E	H	M	L	M	R	V	-	-	-	-	-	P	R	D	G	A	F	L	V	R	K	R	N	E	P	N	-	S	Y	A	I	S	F	R	A	E	G	K	I	K	H	C	R	V	Q	Q	E	-	-	G	Q	-	-	T	V	M	L	G	N	-	S	E	F	D	S	L	V	D	L	I	S	Y	Y	E	K	H	P	L	Y	R	K	M	K	L	R	Y	P	I	N	E	E	A	L	E	K	I	G	T	A

Structures


PDB	Type	Resolution	Domains	Chains	Publication date	Authors	Reference
P19174-AF	Alphafold	-	N-terminal C-terminal	A	2022-06-01	-	-
7NXE	X-ray diffraction	2.100	C-terminal N-terminal	A	2021-06-09	Samarina N., Ssebyatika G. ... Krey T., Schulz T.F.	10.1371/journal.ppat.1009635
4EY0	X-ray diffraction	2.800	C-terminal N-terminal	A B C D	2012-10-31	Bunney T.D., Esposito D. ... Driscoll P.C., Katan M.	10.1016/j.str.2012.09.005
4FBN	X-ray diffraction	2.400	C-terminal N-terminal	A	2012-10-31	Bunney T.D., Esposito D. ... Driscoll P.C., Katan M.	10.1016/j.str.2012.09.005