SH2db - PIK3R2 protein entry

PIK3R2

Recommended name: Phosphatidylinositol 3-kinase regulatory subunit beta

Gene name: PIK3R2

No. of SH2 domains: 2

Uniprot: O00459

Sequences

Protein	Domain	N-term																										bA				bAaA		aA										aAbB				bB								bBbC						bC								bCbD		bD										bDbE		bE			bEbF					bF			bFaB	aB												C-term
																												x50	x51	x52	x53			x42	x43	x44	x45	x46	x47	x48	x49	x50	x51					x45	x46	x47	x48	x49	x50	x51	x52	x49	x50					x47	x48	x49	x50	x51	x52	x53	x54			x47	x48	x49	x50	x51	x52	x53	x54	x55	x56			x48	x49	x50						x48	x49	x50		x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57
PIK3R2	N-terminal	P	K	P	P	K	A	K	P	A	P	T	V	L	A	N	G	G	S	P	P	S	L	Q	D	A	E	W	Y	W	G	D	I	S	R	E	E	V	N	E	K	L	R	D	T	P	D	G	T	F	L	V	R	D	A	S	S	K	I	Q	G	E	Y	T	L	T	L	R	K	G	G	N	N	K	L	I	K	V	F	H	R	D	G	H	Y	G	F	S	E	P	-	L	T	F	C	S	V	V	D	L	I	N	H	Y	R	H	E	S	L	A	Q	Y	N	A	K	L	D	T	R	L	L	Y	P	V	S	K	Y	Q	Q	D
PIK3R2	C-terminal	-	-	-	-	E	T	E	D	Q	Y	A	L	M	E	D	E	D	D	L	P	H	H	E	E	R	T	W	Y	V	G	K	I	N	R	T	Q	A	E	E	M	L	S	G	K	R	D	G	T	F	L	I	R	E	S	S	Q	R	G	-	-	C	Y	A	C	S	V	V	V	D	G	D	T	K	H	C	V	I	Y	R	T	A	T	G	F	G	F	A	E	P	Y	N	L	Y	G	S	L	K	E	L	V	L	H	Y	Q	H	A	S	L	V	Q	H	N	D	A	L	T	V	T	L	A	H	P	V	R	A	P	G	P	G

Structures

PDB

Type

Resolution

Domains

Chains

Publication date

Authors

Reference

Alphafold

-

N-terminal

C-terminal

A

2022-06-01

-

-

X-ray diffraction

1.450

N-terminal

A C E G

2021-08-11

Amelie A., Dai S. ... Zhang X., Cheng X.