SH2db - CBL protein entry

CBL

Recommended name: E3 ubiquitin-protein ligase CBL

Gene name: CBL

No. of SH2 domains: 1

Uniprot: P22681

Sequences

Protein	Domain	N-term																						bA				bAaA		aA												aAbB				bB								bBbC					bC								bCbD		bD										bDbE	aB													C-term
																								x50	x51	x52	x53			x42	x43	x44	x45	x46	x47	x48	x49	x50	x51	x52	x53					x45	x46	x47	x48	x49	x50	x51	x52	x49	x50				x47	x48	x49	x50	x51	x52	x53	x54			x46	x47	x48	x49	x50	x51	x52	x53	x54	x55		x46	x47	x48	x49	x50	x51	x52	x53	x54	x55	x56	x57	x58
CBL	N-terminal	T	R	L	F	Q	P	W	S	S	L	L	R	N	W	N	S	L	A	V	T	H	P	G	Y	M	A	F	L	T	Y	D	E	V	K	A	R	L	Q	K	F	I	H	K	P	G	S	Y	I	F	R	L	S	C	T	R	L	G	Q	W	A	I	G	Y	V	T	A	D	G	N	I	L	Q	T	I	P	H	N	K	P	L	F	Q	A	L	I	D	G	F	R	E	G	F	Y	L	F	P	D	G	R	N	Q	N	P	D	L	T	G	L	C	E	P	T	P	Q	D	H	I	K	V	T	Q	E	Q	Y	E	L	Y	C	E	M	G	S	T	F	Q	L	C	K

Structures


PDB	Type	Resolution	Domains	Chains	Publication date	Authors	Reference
P22681-AF	Alphafold	-	N-terminal	A	2022-06-01	-	-
3BUM	X-ray diffraction	2.000	N-terminal	B	2008-02-26	Ng C., Jackson R.A. ... Guy G.R., Sivaraman J.	10.1038/emboj.2008.18
2Y1N	X-ray diffraction	1.999	N-terminal	A C	2012-01-18	Dou H., Buetow L. ... Vousden K.H., Huang D.T.	10.1038/NSMB.2231
2Y1M	X-ray diffraction	2.670	N-terminal	A B C D E F	2012-01-18	Dou H., Buetow L. ... Vousden K.H., Huang D.T.	10.1038/NSMB.2231
2CBL	X-ray diffraction	2.100	N-terminal	A	1999-05-18	Meng W., Sawasdikosol S., Burakoff S.J., Eck M.J.	10.1038/18050
1YVH	X-ray diffraction	2.050	N-terminal	A	2005-03-08	Hu J., Hubbard S.R.	10.1074/jbc.M414157200
1FBV	X-ray diffraction	2.900	N-terminal	A	2000-08-30	Zheng N., Wang P., Jeffrey P.D., Pavletich N.P.	10.1016/S0092-8674(00)00057-X
1B47	X-ray diffraction	2.200	N-terminal	A B C	1999-04-27	Meng W., Sawasdikosol S., Burakoff S.J., Eck M.J.	10.1038/18050